Tag Archives: genetics

This hidden chemical that causes a deficiency in your brain

Happy Monday Tribe!
I hope you have all had an amazing past couple of weeks! I know its back to school time, and with school back in action, work in full swing, it’s important to talk about hidden toxins that are lurking!

As you now being a brain doc,  I’m always lurking for more information on how to enhance this vital organ that we possess. 

You see, because our brain controls every function in our body we HAVE to do our best to protect it at all costs.

A huge part in creating that healthy brain is of course making sure that environment is working, that VAGUS nerve.  You can take all the supplements in the world but if that nerve isn’t working, you will not get many results.

But, today i’m not talking about cranial work (for once;)), i’m talking about the gut/brain axis and specifically a chemical and many that disrupt this communication.

There’s actually many toxins in your home and that you utilize that you might not know are disrupting this super important connection.

What do you mean gut brain?.  Well, if you’re new here let me explain, for some of my current patients that have been with me awhile, you can sit back for a moment…

Your gut has been termed your “second brain”.  In fact your gut has its entire new network of nerves called the enteric nervous system, that works similar to your brain.

It connects and controls your digestive system, but also has a huge connection in the neurotransmitters in your brain.  It in fact, talks to your actual brain.  A lot of this resides in the health of our gut bacteria to be able to relay that information. So, really you can’t just heal your brain and neglect the rest of your body.

In fact, all the cells of your body talk to one another. So you can’t think that your liver not working won’t cause pain or dysfunction somewhere else.  The cells talk!!

———

So what are things that disrupt this connection?

1. Stress
2. Gluten
3. Processed Foods
4. GMO foods
5. Head Traumas
6. Gut dysbiosis
7. Chemicals
8. EMFs

So, let’s talk about one because of a patient story, so you can see the connection.

I am treating a female patient, and she is doing really well on her protocol, great energy, mostly all her symptoms managed.  She went on a camping trip, and upon her return cancelled her followup because she couldn’t get out of bed.  She said she was wiped out for a few days. I assured her to come in to check on her protocol.  After going through the program, it showed up that their was a titanium toxicity, and she was not making intrinsic factor (i’ll explain in a minute).

I asked her if she applied sunscreen during camping, to which she said yes lots all over my legs. She had the bottle in her car, and we read the back which said ” titanium oxide”. This chemical interfered with her intrinsic factor a glycoprotein that is produced in the stomach, which plays a HUGE role in absorbing vitamin B12. When you can’t use intrinsic factor, it results in a condition called pernicious anemia, which makes sense of why she was tired!.

I gave her some kidney and liver support, and she felt better that next day.
There are so many natural ways to prevent sunburn that don’t include chemicals!

This is just one example, but in reality there are many chemicals we are exposed to all the time!

What else has titanium oxide?

  • Food: Candies, chewing gums, powdered doughnuts, frosting, coffee creamer, vanilla pudding, chocolate bars.
  • Personal Care: Toothpaste, sunscreen, lotions.
  • Misc: Paper, paint, markers, and plastics.


What happens to your brain when you have B12 deficiency ( which can also happen when you have certain genetic mutations) ?!

  • loss of memory
  • cognition problems
  • decreased mood
  • decreased energy
  • Vitamin B12 plays a vital role in the metabolism of fatty acids essential for the maintenance of myelin in the brain.

Again, this is just to show you that all your cells in your body talk to one another!  So what you continually put IN and ON your body matters and makes changes all the way in your brain. 
When the gut in this case is affected (from the chemicals), it sends a signal to the brain to dysfunction.  They HAVE to coordinate with one another.

There’s also a system called the Heart Brain Connection.  Maybe we’ll talk about that next time… stay tuned!

READ BELOW FOR NEXT EO CLASS!

Its Not You, Its Your Hormones….

Happy Monday Tribe!

I hope you all enjoyed last week’s topic about vitamin D and genetics, which was really fitting for the gorgeous weekend we had!

This week, I was to expand a little on genetics, hormone production and weight gain.
Obesity is a leading cause of death worldwide, with increasing rates in adults and children.
•In 2014, 600 million adults (13%) and 42 million children under the age of five were obese.
•From 1971 to 2000, obesity rates in the United States increased from 14.5% to 30.9%.
•More common in women than men.
This is one of the most serious public health problems of the 21st century.

What are the contributors to the recent increase in obesity? 
•Insufficient sleep, increased stress
•Endocrine disruptors, GMO’s
•Increased high fructose corn syrup and sugar consumption
•Sugar substitutes damaging pancreas
•Increased use of medications that can cause weight gain (e.g., atypical antipsychotics)
•Mitochondrial Damage
•Genetic and epigenetic risk factors

SUPER TIP: Where that person stores fat, will determine which hormone/pathway is out of balance: Cortisol directs fat deep in your midsection whereas estrogen directs fat superficially around your hips and thighs (called cellulite).

Let’s talk about 4 particular hormones and their role in our weight:

1. Leptin- produced in fat tissue, it suppresses appetite as its level increases.

2. Ghrelin- secreted by the stomach wall, it triggers feelings of hunger as mealtimes approach. If “dieters” how lose weight, ghrelin increases which may be one reason it’s so hard to stay on a diet.

3. PYY- secreted by the small intestine after meals, acts as an appetite suppressant

4. Insulin– a rise in blood sugar levels after a meal stimulates the pancreas to secrete insulin, which suppresses appetite.

Let’s dive a little deeper……………

 

LEPTIN (hormone)
•Promotes Satiety, thermogenesis, reduces weight
•Reduced by sleep deprivation
•Reduced at night naturally suppressing appetite
•Primarily produced by fat cells
•Increased by emotional stress
•Low calorie diets lower leptin
•LEPR variants can lead to Leptin resistance
•Increases T3 levels

Decrease Leptin:
•Fructose (Esp. HFCS) inhibits Leptin
•Simple Carbs inhibit leptin (through increasing insulin)
•Strict low carb diets inhibit leptin production (need carb loading days)
•Lectins bind leptin receptors (cereals etc)

Increase:
•Omega 3 Fatty Acids (Increase sensitivity)
•Increase fiber (peas, beans, lentils, almonds, raspberries, broccoli, and oats)
•Increase Zinc (spinach, beef, lamb, seafood, nuts, cocoa, beans, mushrooms, and pumpkin)
•Lower Cortisol levels (NET stress work) Or clearing COMT, CBS (genetic pathways)
•Get regular sleep
•Moderate exercise
•Caffeine Improves leptin signaling and receptor activity

GHRELIN
•Synthesized in the gastric mucosa, hypothalamus, pituitary gland, hippocampus, brain cortex, adrenal gland, intestine, pancreas, and many other human tissues.
•Regulates Energy and increases appetite
•Releases growth hormone
•Circulating ghrelin concentration rises before meal and falls after meal. Total ghrelin level increases in night and decreases after breakfast in humans.
•Serum ghrelin increases steadily during long term of fasting and returns to normal after eating.

Increase:
•Estrogen
•Cortisol
•Glucagon
•Insulin-induced hypoglycemia
•Excitation of the vagus nerve can stimulate ghrelin secretion
•Hyperthyroidism

DECREASED:
•Glucose and insulin
•Long chain triglycerides (Essential fatty acids, butter)
•Exercise

Another factor for weight: ADIPONECTIN>

•Adiponectin is a protein which in humans is encoded by the ADIPOQ gene.
•Involved in regulating glucose levels as well as fatty acid breakdown.
•Secreted by adipose tissue
•Increased in calorie restriction, exercise
•Similar to leptin (synergistic)
•Low levels associated with Type II Diabetes, Obesity, Metabolic Syndrome, dyslipidemia, atherosclerosis
•ADHD
•High levels seen in RA


SO we know that for weight and hormone regulation that diet and lifestyle are of course big players.  But what about the genetic role?

According to a study by the Journal of Molecular Endocrinology, 

“Alterations of the normal DNA methylation pattern can contribute to the development of endocrine and metabolic diseases.

Although DNA methylation and demethylation are active processes, epigenetic changes produced during development can impact adult processes, establishing the idea that endocrine function can be persistently affected by events occurring in early life.”

..

Numerous studies indicate that hereditary factors contribute to most of a population’s weight variation, and underscore the statistical difficulties when studying environmental and nutritional effects on body weight.

Here are big gene players with weight:

•FTO, (IRX3), POMC, PCSK, KCTD5, ADIPOQ

FTO for example:
•People with a variation of the FTO gene that affects one in six of the population are 70 per cent more likely to become obese
•People with the obesity-risk FTO variant have higher circulating levels of the ‘hunger hormone’, ghrelin
•Individuals with two copies of the obesity-risk FTO variant are biologically programmed to eat more .

What about other hormones and their relation?
We know that thyroid conditions for instance can directly affect weight loss/gain.
These genes:
•DIO-Converts T4-T3
•TPO-Activates thyroid hormone production
•COMT-Helps breakdown excess cortisol and estrogen that can interfere with thyroid hormone production

All contribute to thyroid up and down regulation, meaning they must be looked at to fully get thyroid conditions in remission.

I won’t bore you with any more genetic information and science words.  What I’m trying to get at with this blog is that there are many factors that can be associated with hormone dys-regulation.

As I mentioned diet, lifestyle and hormone disruptors(below) all play a part.


But, from what we know now, we also have to look into the genetic pathways.  How well can we actually detox these disruptors out?  That lies in your genes. Some of these genes make a person more inclined to lose or gain weight.

 

How do we put it all together:

1.  Watch out for those hormone disruptors. Even your hand soap and hand sanitizers have tricolosan.. read labels.

2. Phase 1 and 2 pathways in the genetic methylation cycles need to be balanced for hormone regulation.

3. Stress modulation– balance the chemistry in the body, and emotional factors

4. Diet and lifestyle OF COURSE.  No gmo non organic foods, processed foods, sugar ect.

Its not always just diet and exercise for people, and as we can see, some people are wired differently than others, and that’s why “universal diets” don’t work well…
Know you’re own body chemistry and you’ll be able to balance those hormones.

Need help?

I’d LOVE to help you with your genetic nutritional help.

Just book an initial nutrition appointment through my website and we will go through it all!

Oil of the Week.

On the spotlight this week is DoTerra’s Slim & Sassy 

The Slim & Sassy Metabolic Blend was specifically designed as a natural way to manage hunger cravings, calm the stomach, and uplift mood.* When used as part of a healthy weight management program and combined with a healthy diet and exercise, the Slim & Sassy oil blend can help boost metabolism and curb hunger cravings.*

Where to Buy Slim & Sassy
If you are pursuing weight loss goals, Slim & Sassy Metabolic Blend can help. Visit our Slim & Sassy oil product page to buy your own today. Along with the Slim & Sassy proprietary blend, doTERRA offers several other Slim & Sassy products, including Slim & Sassy Metabolic Blend SoftgelsSlim & Sassy Control™ Bars and Instant MixSlim & Sassy V Shake, and Slim & Sassy TrimShake. Any of these products can help you on your journey as you strive to create and maintain a healthy lifestyle.

Slim & Sassy Uses and Benefits

  1. When you are working toward a weight loss goal, it can be tough to change your habits and take control of your appetite. Overeating can set you back in your goals for weight management if you aren’t careful, but the Slim & Sassy blend can help control your appetite and keep you from overeating.* Take Slim & Sassy oil internally before meals in order to reduce the likelihood of overeating and to help control your appetite.*
  2. A major benefit of the Slim & Sassy oil blend is its ability to help promote a healthy metabolism.* Those who use the Slim & Sassy Metabolic Blend can rest easy knowing that this proprietary blend is diuretic, stimulant, and calorie-free*—characteristics that can be difficult to find in a weight management product.
  3. A good workout is an important part of any weight loss plan. However, sometimes we lack energy and enthusiasm when we think about working out. Consider adding a few drops of the Slim & Sassy Metabolic Blend to your water or tea before you work out to give yourself a revitalizing energy boost.* The herbal, spicy properties of Slim & Sassy oil will help you perk up and get ready for a successful workout.
  4. The Slim & Sassy blend can be helpful during a weight loss program because it helps the user manage hunger cravings throughout the day.* If you tend to give in to temptation when your body feels a craving sensation, the Slim & Sassy oil blend can help you manage these cravings as they come throughout the day.*
  5. While Slim & Sassy oil was designed to boost metabolism and control cravings, it can also be helpful when you need to calm your stomach* or uplift your mood. As you carry out a weight management plan, you might be changing your diet, which could cause the occasional stomach distress. As you change your diet, exercise plan, and daily routine, you are also bound to feel discouraged or overwhelmed at times. With all of these emotional and physical changes happening, take Slim & Sassy to help calm your stomach troubles* and uplift your mood.
  6. The Slim & Sassy blend can easily be combined with other Slim & Sassy products to help you on your weight loss journey. Consider adding a few drops of Slim & Sassy oil to a Slim & Sassy TrimShake or V Shake. You can blend a single scoop of chocolate or vanilla TrimShake in water, nonfat dairy, almond, rice, or soy milk, and add one drop of Slim & Sassy oil to the mixture for added benefits. If you are using the Slim & Sassy V Shake as part of your weight loss plan, consider adding one drop of Slim & Sassy oil to your morning shake for extra flavor and to help boost your metabolism.*
  7. Because of its vibrant, spicy scent, Slim & Sassy oil can help give you the positive mood you need during a vigorous workout, when used aromatically. Consider diffusing the Slim & Sassy oil blend during your workout to help uplift your mood and give you the positivity you need to keep going. With an invigorating scent nearby, you’ll have the mental and physical strength to make it through your workout.
  8. Slim & Sassy oil can help you manage hunger and control your appetite*, but you may be wondering, “How can I experience these benefits?” To yield the hunger management benefits of the Slim & Sassy blend, try adding eight drops of the oil to 16 ounces of water. When you want help with appetite control, put a few drops of the Slim & Sassy blend in a doTERRA Veggie Capsule and swallow.*

Ingredients

  • Grapefruit Peel
  • Lemon Peel
  • Peppermint Plant
  • Ginger Root
  • Cinnamon Bark

 

That is all for now,

Have a happy and healthy week!

Dr. Hamel

 

Do you take vitamin D?  It may be toxic if you have this gene!

Happy Monday Clan!  I hope you all got information last week about he SB276, you shared and you got fired up about the potential future of our little ones. 

It’s a scary subject, but one that we can’t stand behind anymore.  I hope you got the information you need to continue protesting.

——
This weekend, I went to a LIFE changing seminar.  I’ve been waiting to take a course of advanced genetics and methylation, and this weekend it finally came!  Wow, needless to say I will be changing ALOT in my nutritional practice now knowing what I know.

It seems also pointless for me to go back to doing nutritional protocols without looking at how you are actually processing things.  Today, we will be talking about just 1 gene in the entire pathway shown here.

I know right?!

The body is COMPLEX!  That’s why when people talk about detoxification and MTHFR gene, they miss a big part of the ENTIRE picture.  There’s SO much more than just that one gene, let me tell you!

Don’t worry, before you delete this email from overwhelm, I’m only talking about one gene here called VDR. 

What’s important for you to know as well, is that we cannot change our actual genes, but we CAN change and enhance HOW we express them, which can have huge effects!

For Example:
Recent progress in the understanding of nutritional influences on epigenetics suggests that nutrients that are part of methyl-group metabolism can significantly influence epigenetics.

During critical periods in development, dietary methyl-group intake (choline, methionine, and folate) can alter DNA and histone methylation, which results in lifelong changes in gene expression!!

Also when we are talking about gene regulation through nutrition, the genes we are talking about code for different enzymes.  These enzymes are either unregulated or down regulated causing effects within the body.

VDR is the enzyme responsible for breaking down Vitamin D. If we have a two copies of this gene from mom and dad, then there are extremely limited receptors for vitamin D.

This is how vitamin D converts in our body:
This gene plays an important role in how we can utilize vitamin D!

Which we know is huge for immunity, bone health, and much more.
If you have this gene, and do not have receptors for vitamin D, most likely in your bloodwork you will show low levels of vitamin D.  
But what does that mean?

Well, when you test vitamin D in the blood, that is its inactive form.  What usually happens though is that individuals then start taking vitamin D supplementation.  But this is NOT smart if you have this VDR gene, because you have LIMITED receptors to use it.  So what happens is that the vitamin D gets pulled into the bloodstream and can create calcification in the blood vessels.  

That means you will still be vitamin D deficient, because you’re not using it, but also are creating toxicity in your body by overdosing. 

This gene also has other roles:

-Immune system
-infections
-SIBO
-chronic fatigue
-depression
-Associated with autoimmune diseases such as Hashimoto’s
-Leads to low dopamine levels-depression and reward seeking behavior
-body aches/pains

•Must have methylation cycles going to get full expression of VDR!

IF you know someone with chronic infections, chronic adrenal fatigue or depression, they most likely carry this gene. Giving continual adrenal support, or always detoxing and doing gut protocols will be an endless cycle with these people.  Also, those with LYME you most likely have this gene.  When you REV up this cycle the infections can’t hide!  That means if you have a lot of infections, this cycle isn’t working well if at all.

What needs to be done is add in what are called nutritional co-factors in order to switch that gene’s expression and actually ABSORB the vitamin D!

•Vitamin A protects against vitamin D toxicity and introduced the possibility that vitamins A, D, and K2 may be cooperative factors that should all be consumed in proper balance.

  • Magnesium is needed to exert positive influence over the human genome and may be involved in the genetic actions of vitamin D.
    Magnesium possibly has a role in vitamin D’s effect on the immune system.
    Magnesium works synergistically with vitamin D and calcium by stimulating calcitonin–which helps to preserve bone structure and draws calcium out of the blood and soft tissues back into the bones
  • Fat is also needed to absorb Vitamin D.
  • Vitamin D is absorbed in the small intestine, requires adequate bile salts. Low HCL and food allergies can cause a binding of vitamin D in the small intestine rendering it totally unusable.
  • Probiotic help promote the full absorption of all nutrients, but especially vitamin D.  (Maybe affected by FUT variants.)
  • VDR balancing can help heal SIBO and greatly benefit the microbiome.
VITAMIN D BLOCKERS:

•Cortisol
•Caffeine-Don’t take Vit D.  with coffee
•Gallbladder issues-Decreases absorption of fat soluble vitamins (ADEK)
•Infections can reduce or block VDR function

 

So, think TWICE before taking just a vitamin D supplement when your vitamin D levels are low.  Make sure you know your genetics.  I like using ancestry.com, and decoding them from there.

More to come on other important genes, and how to clean them up!

I’m excited to incorporate this more and give patients LESS supplements, more SPECIFIC supplements at the cellular level to make lasting changes to allow YOUR body to do what it needs to do.

Have a great week!

Oil of the Week.

On the spotlight this week is DoTerra’s Lemongrass.

What are the origins of a plant’s unique essential oil? The answers lie in genetics. Genes function as a code, similar to the code that runs an app. If you know how to read an app’s code, you can construct in your mind the various functions, and the look and feel of the app. The same applies to genes. Scientists have made great strides in knowing how to read what a gene’s code will make.

 

DNA is a sequence of linked nucleotides, which are a form of small molecule. A gene is a cluster of these nucleotides. It used to cost billions of dollars and years of extremely hard work to sequence the genes of an organism. In the last 20 years, sequencing technology has improved dramatically, such that now sequencing genes is quick and relatively inexpensive. Scientists have found that most genes code for distinct proteins. Proteins perform almost all of the functions of a cell, including producing the various chemical components of an essential oil.

 

Scientists in India studied the genetic origins of Lemongrass essential oil, which is native to India. Lemongrass, Cymbopogon flexuosus, produces many secondary metabolites, including essential oils. Of the genes relating to secondary metabolites, 18 percent coded for terpenoid backbone biosynthesis, 1 percent for monoterpenoid biosynthesis, 1 percent for sesquiterpenoid and triterpenoid biosynthesis, and 5 percent for limonene and pinene degradation. That represents a significant investment by the Lemongrass plant in producing a diverse essential oil. The diversity of these genes correlates to the diversity of components in Lemongrass essential oil.

 

It is theorized that plants with more diverse essential oil component profiles also have a diverse profile of essential oil biosynthesis genes. The chemical component makeup of a plant’s essential oil isn’t created by chance, but is due to evolutionary pressures working on the genes of the plants over time. The essential oil of Lemongrass (and other plants) are therefore the product of thousands of years of evolutionary selection to give you the very best that nature has to offer.

 

 

 

 

 

Nutrition, Bugs and Genetics…. Adrenal Depleters

Happy Monday!  It’s newsletter time!  And we are talking this month all about adrenals!!  Last week, we chatted about how mechanical dysfunction within your brain and nervous system depletes the adrenal glands.

This week we will be talking about nutritional deficiencies, Bugs and Genetics that can come into play and affect the health of your adrenal glands.

Are you ready?

Lets dig in!

Step 1.  Nutrition.

As mentioned in our first blog about adrenals, the adrenal glands secrete steroid hormones.  Steroid hormones come from cholesterol!

In order to have proper hormone function, we need to have proper fat absorption and utilization within the body.  Our hormones rely on fat, and a healthy balance of it.

As mentioned, cholesterol IS NOT BAD.  It is actually a superhero with many vital functions.  If we don’t get enough adequate cholesterol within our diet, our storage will start to rev up.  Again this is VITAL.  A good blood marker is around 180-220.  THIS IS NORMAL.  Lower levels and you will have significant hormone problems.  

If your cholesterol is higher than 220, then it is either a liver problem, genetic(rare), or the excess cholesterol is trying to put out a fire in your body .  You see cholesterol goes to area of the body where there is inflammation and tries to patch it up.  ( this is why cholesterol goes to arteries that are weak and inflamed and tries to patch it up).  It’s the superhero, not the culprit.  So we need to figure out what those flames are, which leads into our next portion.

Also important, if you have food allergies, these are CHRONIC adrenal gland depleters.  Sometimes they aren’t actual allergies, but inflamed digestive tracts from pathogens.  Once the pathogens are cleared the nervous system and inflammation will calm down, and the food sensitivities can go away.

I can desensitize certain allergies through craniobiotic technique in my office.  But a good rule of thumb is to eliminate gluten and pasteurized dairy if you have adrenal fatigue.  These are inflammatory for EVERYONE and shouldn’t be consumed, but especially for those with adrenal problems.

GMO and non organic foods are also problems.  We can’t digest GMO foods, they are foreign to our body.  And non organic foods have thousands of chemicals and pesticides which means more adrenal stress.

2. BUGSS.

Did you know the prevalence of Esptein Barr Virus or Mono? In the research conducted in 2005, it was found that Epstein-Barr Virus (EBV) infects more than 98 percent of the world’s population!  Yep.

Know anyone with ulcerative colitis or Chrons?
Almost ALL causes of ulcerative colitis or Chron’s disease show positive for Mycobacterium species.

Alzheimers or MS?
Lyme Disease Bacteria has been shown to be prevalent in cadaver’s brains in Alzheimers patients, and MS can be misdiagnosed for the borrelia bacteria.

Chronic diarrhea or IBS?
You most likely have a protozoal/amoeba infection.

Almost every single nutrition patient that comes to me has parasites.  Its actually NOT normal to find someone without these days.  Things are all around.

I could go on… the fact of the matter is that almost ALL diseases can be traced to BUGS.  Things don’t just “happen”.  Auto-immune diseases don’t just “happen”.  Usually the gut/brain pathways are stressed through pathogens and nervous system distress.  Pathogens like microbes can hide in our bodies for years and wreak havok creating chronic stress and adrenal depletion.

It’s important to note, a lot of infections go undiagnosedThat’s because typical blood work and even stool testing doesn’t always find these hidden pathogens.  Testing isn’t perfect.

Thankfully I have functional medicine tools to use including Craniobiotic Technique to screen for these hidden pathogens.

You HAVE to take care of stealth pathogens, because they are chronic immune system and energy depleters.  
It’s also important to know that when you are killing these bugs, if you are able to actually eliminate them out of your body.  If you aren’t then you will have a lot of side effects, and it could be harmful.  We have to get pathogens and toxins OUT the shooter.

Which leads to Step 3.

Step 3.  Genetics

Genetics have been all the “rave” the past 5-10 years as we learn more and more about them.  It’s important to note the difference between genetics and epigenetic.  Epigenetics are specific genes we have that may be turned “on” or “off”.  But, the great thing is that we can change our epigenetics.  We know that the food we eat, environment that we are in, emotional stability all have effects on our genes. 

With genetics, specifically with the adrenal glands, if you have chronic adrenal fatigue, sometimes looking into genetics is necessary.

This is mainly because it you have a lot of genes that aren’t functioning well, then the pathways that we need are not functioning well.  Add in infections, nervous system stress and emotional instability and it’s a trifecta of improper detoxing.   Most of what we are looking at with the genetics here is the function of enzymes.

So, in these cases, genetics are very useful.

One gene in particular is called the MTHFR gene.  (yep that’s how its spelled!).  It stands for methylenetetrahydrofolate reductase.  With this gene mutation (you can have many forms), you cannot convert a B vitamin called folic acid to folate which is the end product we need to make methylation (detoxing) happen.  So this enzyme is impaired.  That means ingesting folic acid in supplements is very toxic and harmful to this person because they can’t break it down to the end product folate.

So why is folic acid in supplements?  SYNTHETIC supplements contain folic acid (which I NEVER use) because it’s cheap.  It’s way better to use whole food supplements or ones that have FOLATE instead of folic acid.

Good to know right?

Absolutely!  Genes give us more information!

B vitamins are essential for many things, but ENERGY is a huge one.  If you can’t synthesize your B vitamins, you won’t detox well and your adrenals and energy will suffer.

This is just one example of how a gene could affect adrenal function.

Genes can affect neurotransmitters and mood disorders, and also other B vitamins.

It gets more complicated as we go, so it’s important to chat with someone who is versed in genes.  A great resources is the book “dirty genes” By Dr. Ben Lynch.  Meaning we need to clean up these dirty gene pathways to experience health and vitality!

So what to do???

Functional Nutrition is key.  Sometimes we need to support the adrenal glands with nourishing herbs and whole foods while we are cleaning out the bugs, clearing nervous system and emotional stress and working on the genetic pathways.  Also, with genes it’s not about giving supplements for every little gene mutation.  This is a big no no. It’s about looking at the whole picture.
Genes just give us more information, but remember we can change gene epigenetics!  Changing the diet is key, and stabilizing the blood sugar is number one.

I recommend a more Ketogenic high fat and low carb lifestyle.  With moderation for everyone with different needs.   Cutting out dead carbs will stabilize blood sugar and allow the body to burn fat.

A yo yo of glucose going up and down stresses out the adrenal glands immensely, so this is one of the first things that needs to be addressed.

Looking at the diet, when you are eating, and supporting as needed. Many people are deficient in vitamins and minerals and don’t even know it. Minerals, such as chromium and magnesium are essential to keeping blood sugars in the normal range. Also important to not eat sweets when you get that energy crash.. This is where herbal support comes in!  Eating a good fat/protein before bed will actually make you sleep better too!!

Often times people have insomnia because their blood sugar is so unbalanced.  They wake up multiple times in the night because they actually are starving.  Eating carbs will only suffice you for a few hours.   If you wake up tired, and go to bed energized, then your adrenals are ALLL kinds of messed up, and you need some help!

I’m happy to help!